人才队伍
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人才信息
姓名:
 叶明亮
性别:
 男
类别:
 研究员;杰出青年;百人
学科:
 应用化学
职称:
 研究员
学历:
 博士研究生
电话:
 0411-84379620
Email:
 mingliang@dicp.ac.cn
地址:
 大连市中山路457号
邮编:
 116023
简历介绍:
    叶明亮,2001年8月在中科院大连化学物理研究所获博士学位,并获中科院院长特别奖。2001年年底赴美国华盛顿大学化学系从事博士后研究,主要进行生物分子的高灵敏度荧光检测与高效分离方面的研究,2003年初来到美国系统生物研究所从事高通量蛋白质组学方面的研究。2004年年底回到中国科学院大连化学物理研究所并入选中科院 “百人计划”。
研究方向:
职务:
社会任职:
获奖及荣誉:
代表论著:

  1. Mingliang Ye*, Yanbo Pan, Kai Cheng, Hanfa Zou*. Protein digestion priority is independent of protein abundances. Nature Methods, 2014, 11,220-222

  2. Fangjie Liu, Mingliang Ye*, Yanbo Pan, Yi Zhang, Yangyang Bian, Zhen Sun, Jun Zhu, Kai Cheng, Hanfa Zou* Integration of Cell Lysis, Protein Extraction, and Digestion into One Step for Ultrafast Sample Preparation for Phosphoproteome Analysis. Analytical Chemistry, 2014, 86, 6786?6791

  3. Chunxia Song, Fangjun Wang, Kai Cheng, Xiaoluan Wei, Yangyang Bian, Keyun Wang, Yexiong Tan, Hongyang Wang, Mingliang Ye*, Hanfa Zou*. Large-Scale Quantification of Single Amino-Acid Variations by a Variation-Associated Database Search Strategy. Journal of Proteome Research, 2014, 13, 241-248

  4. Yangyang Bian, Chunxia Song, Kai Cheng, Mingming Dong, Fangjun Wang, Junfeng Huang, Deguang Sun, Liming Wang, Mingliang Ye*, Hanfa Zou*. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. Journal of Proteomics, 2014, 96, 253-262

  5. Yanbo Pan, Mingliang Ye*, Hao Zheng, Kai Cheng, Zhen Sun, Fangjie Liu, Jing Liu, Keyun Wang, Hongqiang Qin, Hanfa Zou*. Trypsin-Catalyzed N?Terminal Labeling of Peptides with Stable Isotope-Coded Affinity Tags for Proteome Analysis. Analytical Chemistry, 2014, 86, 1170-1177

  6. Zhen Sun, Deguang Sun, Fangjun Wang, Kai Cheng, Zhang Zhang, Bo Xu, Mingliang Ye*, Liming Wang*, Hanfa Zou. Differential analysis of N-glycoproteome between hepatocellular carcinoma and normal human liver tissues by combination of multiple protease digestion and solid phase based labeling. Clinical Proteomics, 2014, 11:26, 1-11.

  7. Kai Cheng, Rui Chen, Deeptee Seebun, Mingliang Ye*, Daniel Figeys*, Hanfa Zou. Large-scale characterization of intact N-glycopeptides using an automated glycoproteomic method. Journal of Proteomics, 2014, 110, 145-154

  8. Jun Zhu, Fangjun Wang, Kai Cheng, Chunxia Song, Hongqiang Qin, Lianghai Hu, Daniel Figeys, Mingliang Ye*, Hanfa Zou*. Analysis of human serum phosphopeptidome by a focused database searching strategy. Journal of Proteomics, 2013, 78, 389-397

  9. Houjiang Zhou#, Mingliang Ye#, Jing Dong, Eleonora Corradini, Alba Cristobal, Albert J R Heck*, Hanfa Zou*, Shabaz Mohammed*. Robust phosphoproteome enrichment using monodisperse microsphere–based immobilized titanium (IV) ion affinity chromatography. Nature Protocols, 2013, 8,3,461-480

  10. Fangjie Liu, Mingliang Ye*, Chunli Wang, Zhengyan Hu, Yi Zhang, Hongqiang Qin, Kai Cheng, Hanfa Zou*. Polyacrylamide Gel with Switchable Trypsin Activity for Analysis of Proteins. Analytical Chemistry, 2013, 85,7024-7028

  11. Chunli Wang, Mingliang Ye*, Yangyang Bian, Fangjie Liu, Kai Cheng, Mingming Dong, Jing Dong, Hanfa Zou*. Determination of CK2 Specificity and Substrates by Proteome-Derived Peptide Libraries. Journal of Proteome Research, 2013, 12, 3813-3821

  12. Yanbo Pan, Mingliang Ye*, Liang Zhao, Kai Cheng, Mingming Dong, Chunxia Song, Hongqiang Qin, Fangjun Wang, Hanfa Zou*. N-Terminal Labeling of Peptides by Trypsin-Catalyzed Ligation for Quantitative Proteomics. Angewandte Chemie-International Edition, 2013, 52, 9205-9209

  13. Yangyang Bian, Mingliang Ye*, Chunli Wang, Kai Cheng, Chunxia Song, Mingming Dong, Yanbo Pan, Hongqiang Qin, Hanfa Zou*. Global Screening of CK2 Kinase Substrates by an Integrated Phosphoproteomics Workflow. Scientific Reports, 2013, 3, 3460, 1-7

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